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Twenty, six children younger than 15 years with severe aplastic anemia underwent either bone
marrow transplantation or immunomodulation therapy (antilymphocyte globulin with cyclosporin A
therapy).
Six patients who had an HLA-identical sibling donor underwent bone marrow transplantation after
conditioning with cyclophosphamide, procarbazine and antilymphocyte globulin. Twenty children
who did not have an HLA-identical donor recieved antilymphocyte globulin and cyclosporin A.
The results were as follows;
1) Hematologic responses:... |